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Structural Biology Core

 

As a core structural biology laboratory at Dana-Farber Cancer Institute, we collaborate with DFCI and Harvard Medical School laboratories to test biological, biochemical, and chemical hypotheses using in-vitro experiments, including those listed below, resulting in medical research publications listed in PubMed. If you are looking for a partner and collaborator that can help test your emerging mechanistic and clinical hypotheses with structural biology and associated experiments, please contact us.

  • Recombinant protein expression and purification
  • Biophysical and biochemical characterization and mechanism-of-action studies
  • Crystallization of apo and liganded targets, and structure determination